Pathogenesis of Presbyopia: A New Understanding of an Age-Old Disease
FOR MOST OF HISTORY, PRESBYOPIA has been defined as a “normal” refractive error caused by age, with discussion limited to the loss of near vision beginning in our 40s. Because we have had no effective therapeutic interventions available, presbyopia has been accepted as a natural part of life and treated primarily by changing power at either the cornea or the lens, hallmarked with some type of visual compromise. The reality is that presbyopic solutions have failed to adequately address this large unmet market, frustrating both physicians and industry. This has led to a waning interest in presbyopic treatments and a currently empty space for devices and therapeutics to treat this growing population. Recent developments in pharmacological presbyopia therapeutics have sparked a renewed enthusiasm in the advancement of presbyopia treatments. However, the real etiology of the loss of accommodative function and its impact on the eye as we age – beyond just the loss of near vision – has yet to be addressed. As we enter this exciting new age of presbyopia therapeutics, it is essential to understand the complex pathophysiology of the aging eye, as well as the pathogenesis of biomechanical dysfunction of accommodation. Illuminating these pathogeneses must be achieved to realize an effective approach to this progressive disease, which to a large extent has age-related biomechanical implications.
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Jackson discusses laser scleral microporation for presbyopia
LAS VEGAS — In this Healio Video Perspective from the ASCRS meeting, Mitchell A. Jackson, MD, discusses preliminary results from a trial investigating laser scleral microporation to treat presbyopia.
read moreProfessor Marshall Continues to Propel Ace Vision Group Forward
Ace Vision Group, Inc., an emerging medical device company at the forefront of pioneering rejuvenation therapy for the aging eye, today announced that it has named John Marshall, PhD, FRCPath, FMedSc as Scientific Advisor of Laser Technology. Professor Marshall is a pioneer of laser eye surgery, having developed computer-controlled excimer lasers for the correction of …
read moreTHE ZOOMING EYE LENS: Effects of Age on Dynamic Range of Focus
DYNAMIC RANGE OF FOCUS (DRoF), or the total range of clear vision in a natural system, is an important biomechanical function of the accommodative apparatus responsible for adjusting the crystalline lens from both far to near (accommodation) and near to far (disaccommodation). DRoF is defined by true accommodation, pseudoaccommodation, and pupillary diaphragmatic changes, which work together …
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